Tricalcium Phosphate, β-TCP
Name: Tricalcium phosphate
Molecular Formula:Ca3(PO4)2
Molecular Weight:310.18
CAS No.:7758-87-4
White powder;
2-10μm；98%
Beta tricalcium phosphate (β-TCP) has good biodegradability, biocompatibility and osteoinductive ability. After being implanted into the human body, the degraded calcium and phosphorus can enter the circulation system of the living body to form new bone, so it is widely used. Repair bone tissue. However, it has poor toughness, is easily brittle, and has poor load carrying capacity. Poly-L-lactic acid (PLLA) has also been used in bone tissue repair due to its good biocompatibility and biodegradability.
Tricalcium phosphate has good biocompatibility, bioactivity and biodegradability. It is an ideal human hard tissue repair and replacement material and has been receiving close attention in the field of biomedical engineering. What is commonly used in medicine is a special form of tricalcium phosphate - beta-tricalcium phosphate.
β-Tricalcium phosphate is mainly composed of calcium and phosphorus. Its composition is similar to the inorganic components of bone matrix and combines well with bone. Animal or human cells can grow, differentiate and reproduce normally on β-tricalcium phosphate materials. A large number of experimental studies have proven that β-tricalcium phosphate has no adverse effects on bone marrow hematopoietic function, no rejection reaction, no acute toxic reaction, no carcinogenesis, and no allergic phenomenon. Therefore, β-tricalcium phosphate can be widely used in joint and spinal fusion, limb trauma, oral and maxillofacial surgery, cardiovascular surgery, and filling of periodontal cavities. As people's research on β-tricalcium phosphate continues to deepen, its application forms have also become diversified, and it has demonstrated better performance in clinical medicine.
The degree of hemolysis is <5%. When β-tricalcium phosphate is implanted into the human body, it can be degraded and absorbed in body fluids. Calcium and phosphorus are absorbed by body fluids and enter the human circulation system. After a certain period of time, β-tricalcium phosphate is implanted in the human body. The tricalcium gradually dissolves and disappears, forming new bone. Compounding β-tricalcium phosphate with autologous bone marrow is an ideal method for treating bone defects. After implantation, there is no obvious inflammation or other reactions in local tissues. As a carrier of anti-tuberculosis drugs and antibiotics, it is packed into the affected area of osteomyelitis and the defective bone is basically repaired.
Application: This material can be used for scientific research and teaching experiments in universities, 3D printing and molding in the medical industry, traditional ceramic manufacturing, bone tissue defect filling and repair, etc.
